ENROXAN-100 ( ORAL )
Antibiotic oral solution
Composition
100 ml of preparation contains active substance Enrofloxacin – 10.0 g; Additional ingredients.
Pharmacological properties
Enrofloxacin is a chemotherapeutic preparation belonging to the group of fluoroquinolones (derivative quinolone-carboxylic acid). Enrofloxacin shows antimicrobial activity by inhibiting enzyme activity of DNA gyrase, which is a major catalyst for replication of DNA in bacterial cell. Inhibiti of DNA gyrase activity leads to functional disorders, blocking biosynthesis in cell and destruction of pathogen. The result is a rapid bactericidal effect, particularly against microorganisms resistant to beta-lactam antibiotics, tetracyclines, aminoglycosides and macrolides.
Enrofloxacin is effective against different types of microorganisms: Mycoplasma spp., E. coli, Salmonella spp., Campylobacter spp., Haemophilus spp., Pasteurella spp., Bordetella spp., Klebsiella spp., Streptococcus spp., Enterococcus spp., Erysipelothrix rhusiopathiae, Proteus spp., Vibrio parahaemolyticus, Staphylococcus aureus.
Administration
Treatment of swine, calves (up to 3 months of age) with mycoplasmosis, wound and secondary infections, as well as respiratory, digestive and urinary tract diseases and skin damages, caused by microorganisms susceptible to Enrofloxacin.
Treatment of domestic poultry (broilers, breeding chickens, replacements and turkeys) with colibacillosis, mycoplasmosis, salmonellosis, pasteurellosis, staphylococcal and streptococcal infections caused by microorganisms susceptible to Enrofloxacin.
Routes of administration and dosages
Orally in drinking water at doses:
|
Animal species, including poultry |
Dose by active ingredient (mg/kg b.w.) |
Dose of ENROXAN-100 for oral use |
|
|
ml/10 kg b.w. |
ml/1 L water |
||
|
Domestic poultry (broilers, breeding chickens, replacements and turkeys) |
5,0 – 10 |
– |
0,5-1,0 |
Duration of treatment – 3-5 days, in cases of salmonellosis, pasteurellosis and mixed infecti – 5-10 days. During treatment, birds should only receive water containing medicament. Every day it’s necessary to prepare fresh solution of the preparation.
Withdrawal period
Meat of animals in 12 days and poultry in 11 days after the last treatment. Meat received before this time should be disposed or fed to non-productive animals, depending on conclusion of veterinarian.
Self life
24 months. After first opening – 14 days if kept in dark place at +5 to +25° С.
Storage conditions
Store in dry, dark places, out of the reach of children, at +5 to +25° С.